the extract of crocus sativus and its constituent safranal, affect serum levels of endothelin and total protein in sensitized guinea pigs
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abstract
objective(s): the effect of the extract of crocus sativus and its constituent, safranal on inflammatory markers in sensitized guinea pigs was examined. materials and methods: ovalbumin (oa) sensitized guinea pigs were given drinking water alone (group s), or drinking water containing three concentrations of safranal, three concentrations of extract and one concentration of dexamethasone, (n=6, for all groups) and serum levels of endotheline-1 (et-1) and total protein (tp) were assessed. results: serum levels of et-1 and tp in group s were significantly higher than control group (p conclusion: a preventive effect of the extract of c. sativus and its constituent safranal on serum inflammatory markers in sensitized guinea pigs was shown.
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The Extract of Crocus sativus and Its Constituent Safranal, Affect Serum Levels of Endothelin and Total Protein in Sensitized Guinea Pigs
Objective(s): The effect of the extract of Crocus sativus and its constituent, safranal on inflammatory markers in sensitized guinea pigs was examined. Materials and Methods: Ovalbumin (OA) sensitized guinea pigs were given drinking water alone (group S), or drinking water containing three concentrations of safranal, three concentrations of extract and one concentration of dexamethasone, (n...
full textThe Extract of Crocus sativus and Its Constituent Safranal, Affect Serum Levels of Endothelin and Total Protein in Sensitized Guinea Pigs
OBJECTIVE(S) The effect of the extract of Crocus sativus and its constituent, safranal on inflammatory markers in sensitized guinea pigs was examined. MATERIALS AND METHODS Ovalbumin (OA) sensitized guinea pigs were given drinking water alone (group S), or drinking water containing three concentrations of safranal, three concentrations of extract and one concentration of dexamethasone, (n=6, ...
full textThe Effect of Carvacrol on Serum Cytokines and Endothelin Levels of Ovalbumin Sensitized Guinea-Pigs
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previous studies have indicated relaxant, inhibitory effect on histamine (h1) and muscarinic receptors, and stimulatory effect on β-drenoceptor of crocus sativus on guinea pig tracheal chains. in the present study, the effect of the extract of c. sativus and one of its constituents, safranal, on the inflammatory changes of sensitized guinea pigs was examined. eight groups of sensitized guinea p...
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Journal title:
iranian journal of basic medical sciencesجلد ۱۶، شماره ۹، صفحات ۱۰۲۲-۱۰۲۶
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